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Module Name: Diffusive Barriers in Purkinje Neuronal Spines
Author(s): Sherry Ann Brown
Institutions: University of Connecticut Health Center, Farmington, CT
Module Biology Topic: Biochemical Reactions and DIffusive Behaviours
Other Biology:  
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UG Course Level: Beginner
Tool(s): Virtual Cell
Other tool: Vcell.org or VirtualCellPage
Module Created: 2009/07/01
Status Started

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Abstract These exercises accompany the chapter “Spatial Organization and Diffusion in Neuronal Signaling” to appear in an edited text by Le Novere, published by Springer. They are designed to guide the reader through the exploration of restricted diffusion and compartmentalization in three different dendritic spines with unique morphologies in a constructed and experimentally derived 3D geometry. Although constructed with early versions of Virtual Cell, the models are accessible and valid in later version. Up to date instructions on how to view, run and save models can be found in the Virtual Cell User Guides at http://www.vcell.org/.
Physiology biochemical reactions, dendritic spines, IP3 signaling
Model description Deterministic models
Model files  
Model exercises BrownetalExercises.pdf
Further reading and references: Brown public models

CategoryModule -- RaquellHolmes - 2011-03-17

Topic attachments
I Attachment Action Size Date Who Comment
PDFpdf BrownetalExercises.pdf manage 74.9 K 2011-07-06 - 18:54 RaquellHolmes Exercises in VCell for reaction diffusion in neuronal spines
Topic revision: r4 - 2011-07-06 - 19:00:12 - RaquellHolmes
 
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